California State University San Bernardino Department of Computer Science and Engineering Masters Thesis Defense Date Monday February 23th, 2009 Time 10:00am-11:00am Location JB-391/389 Title Efficient Proton Computed Tomography Image Reconstruction Using General Purpose Graphics Processing Units Candidate Scott McAllister Advisor Dr. Keith Schubert Committee Members Dr. Ernesto Gomez Dr. Richard Botting Dr. Reinhard Schulte Abstract Proton Computed Tomography (pCT) is an imaging modality that is based on the tracking of individual protons as they traverse an object. These paths deviate from a straight line due to the effects of multiple Coulomb scattering (MCS) and must be tracked using a formalism that models MCS. A sparse iterative solver, like the algebraic reconstruction technique (ART), is used to reconstruct the object using these non-linear paths. Because sparse iterative solvers are slow, parallel algorithms, executed simultaneously over multiple processing units are required. This thesis will investigate the use of general purpose graphics processing units (GPGPUs) for execution of these parallel algorithms as well as exploiting the structure of the data being processed. From the results, recommendations for new research directions will be suggested.